The Liver Takes It All

The risk of liver damage is one of the biggest challenges to the development and approval of new medications. Researchers at the Hamner Institutes are developing a mathematical model of metabolite biomarkers to better predict drug-induced liver injury, or DILI.

NGSS Performance Expectation: Design a solution to a complex real world problem by breaking it down into smaller, more manageable problems that can be solved through engineering.

Discussion Questions:

  1. What does the liver do?
  2. What is a hepatic lobule?
  3. What is the big problem the researchers in the video are intent on solving?
  4. How is this big problem being broken down into more manageable pieces?
  5. How does drinking alcohol impact the liver?
  6. How does too much acetaminophen impact the liver?

 

GlaxoSmithKline

UNC-TV Media